BioResearch Group (BRG) is conducting a medical experiment aimed at assessing nicotine concentrations following the use of new tobacco-free heated non-burning (HNB) products, compared with other categories of nicotine products in healthy volunteers.

The study is designed as a randomized, controlled, open-label trial using a crossover design. This means that each study participant uses all evaluated product categories in a different sequence, allowing for a precise comparison of nicotine exposure within the same individual.

The primary focus of the analysis is the assessment of blood nicotine concentrations, as well as the safety and tolerability of the investigated products. All procedures are carried out under strict medical supervision, in accordance with applicable legal regulations and the principles of Good Clinical Practice (GCP).

Research on nicotine products conducted at BioResearch Group focuses on the scientific evaluation of their properties and the potential development of new, alternative solutions to traditional, most harmful tobacco products. The data generated through these studies contribute to the advancement of knowledge in the field of public health and provide important support for regulatory assessment processes.